The American Dental Association's October 2025 guidance for patients on these peptides spells out the cascade: GI side effects (nausea, vomiting, reflux) lower the pH inside the mouth, and lower oral pH eats at tooth enamel.

Saliva normally buffers the acid; when saliva drops, the defense drops with it. So the path is peptide → GI side effects → low oral pH → enamel erosion.

The "Ozempic teeth" framing names a real cluster of dental problems, but with the wrong cause. The dentist-facing literature treats the issue as preventable through routine dental care and attention to reflux.

There isn't a peptide-specific dental mechanism in the evidence. The chain is the GI side effects.