Fertility is shaped by weight, metabolic health, menstrual regularity, ovarian function, age, sleep, other medications, and underlying conditions. For people with weight-related fertility problems, weight loss can support a return of regular cycles.

For people in a steep calorie deficit, fertility signals can shift the other way. That's a property of the deficit, not specific to these peptides.

The Wegovy label is direct on pregnancy planning: stop the medication at least two months before a planned pregnancy because the peptide has a long half-life and stays in the body for weeks after the last dose.

The signal in the label is a planning window, not a fertility outcome.